Howtoforge posted a guide about integrating ClamAV into PureFTPd on Debian 5.0

This tutorial explains how you can integrate ClamAV into PureFTPd for virus scanning on a Debian Lenny system. In the end, whenever a file gets uploaded through PureFTPd, ClamAV will check the file and delete it if it is malware.

How To Integrate ClamAV Into PureFTPd For Virus Scanning On Debian Lenny