Howtoforge published a guide about setting up Nginx with PHP5 on OpenSUSE 12.1

Nginx (pronounced "engine x") is a free, open-source, high-performance HTTP server. Nginx is known for its stability, rich feature set, simple configuration, and low resource consumption. This tutorial shows how you can install Nginx on an OpenSUSE 12.1 server with PHP5 support (through PHP-FPM) and MySQL support.

  Installing Nginx With PHP5 (And PHP-FPM) And MySQL Support On OpenSUSE 12.1