Howtoforge posted a guide about setting up Fedora 10 with ISPConfig 3

This tutorial shows how to prepare a Fedora 10 server for the installation of ISPConfig 3, and how to install ISPConfig 3. ISPConfig 3 is a webhosting control panel that allows you to configure the following services through a web browser: Apache web server, Postfix mail server, MySQL, MyDNS nameserver, PureFTPd, SpamAssassin, ClamAV, and many more.

The Perfect Server - Fedora 10