Howtoforge posted a tutorial about setting up Fedora 14 x86_64 with ISPConfig 2 as server

This is a detailed description about how to set up a Fedora 14 server that offers all services needed by ISPs and hosters: Apache web server (SSL-capable) with PHP5/Ruby/Python, Postfix mail server with SMTP-AUTH and TLS, BIND DNS server, Proftpd FTP server, MySQL server, Dovecot POP3/IMAP, Quota, Firewall, etc.

This tutorial is written for the 64-bit version of Fedora 14, but should apply to the 32-bit version with very little modifications as well.

In the end you should have a system that works reliably, and if you like you can install the free webhosting control panel ISPConfig (i.e., ISPConfig runs on it out of the box).

  The Perfect Server - Fedora 14 x86_64 (ISPConfig 2)