Howtoforge posted a tutorial about setting up Ubuntu 11.10 with Nginx and ISPConfig 3

This tutorial shows how to prepare an Ubuntu 11.10 (Oneiric Ocelot) server with nginx for the installation of ISPConfig 3, and how to install ISPConfig 3. Since version 3.0.4, ISPConfig comes with full support for the nginx web server in addition to Apache, and this tutorial covers the setup of a server that uses nginx instead of Apache. ISPConfig 3 is a webhosting control panel that allows you to configure the following services through a web browser: nginx and Apache web server, Postfix mail server, MySQL, BIND or MyDNS nameserver, PureFTPd, SpamAssassin, ClamAV, and many more.

  The Perfect Server - Ubuntu 11.10 With Nginx and ISPConfig 3